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Nalidixic acid sodium salt is an antibacterial agent, which is inhibitor of bacterial DNA polymerase & avian myeloblastoma virus reverse transcriptase. The compound inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Nalidixic acid is a monocarboxylic acid and quinoline antibiotic
• Nalixidic acid is a DNA synthesis inhibitor that acts by preventing DNA gyrase activity
Application
• Nalidixic acid is most effective against gram-negative bacteria, including Enterobacter species and other common resistant species
• It is suitable in laboratory applications for research of the mechanisms of gyrase activity and metabolic pathways related to DNA synthesis