Captopril, Thermo Scientific Chemicals
Captopril, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Captopril, Thermo Scientific Chemicals

Orally active inhibitor of angiotensin-converting enzyme
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Catalog number J63593.03
also known as J63593-03
Price (USD)/ Each
72.30
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Quantity:
1 g
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Price (USD)/ Each
72.30
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Captopril, Thermo Scientific Chemicals
Catalog numberJ63593.03
Price (USD)/ Each
72.30
-
Add to cart
Chemical Identifiers
CAS62571-86-2
IUPAC Name(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Molecular FormulaC9H15NO3S
InChI KeyFAKRSMQSSFJEIM-RQJHMYQMSA-N
SMILESC[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Assay (HPLC)80.0% min.
Residue on ignition0.2% max
Melting Point104-110?C
Appearance (Color)White to off-white
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Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density. Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density. Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity

Solubility
Soluble in water (160 mg/ml) at 25°C, sesame and corn oils (<1mg/mL) at 25°C, methanol (>100 mg/ml), ethanol (>100 mg/ml), isopropanol (>100 mg/ml), chloroform (>100 mg/ml), and dichloromethane (>100 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Andrew S Greene; Sandra L Amaral. Microvascular angiogenesis and the renin-angiotensin system. Current Hypertension Reports. 2002, 4 (1), 56-62 .
  2. N K Hollenberg. Renal implications of angiotensin receptor blockers. American Journal of Hypertension. 2001, 14, 237S-241S.