Thermo Scientific Chemicals

Carbenoxolone disodium salt, 97+%, Thermo Scientific Chemicals

Catalog number: J63714.06
5 g, Each
Thermo Scientific Chemicals

Carbenoxolone disodium salt, 97+%, Thermo Scientific Chemicals

Catalog number: J63714.06
5 g, Each
Quantity
Catalog number: J63714.06
also known as J63714-06
Price (USD)
Quantity
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Chemical Identifiers

CAS
7421-40-1
IUPAC Name
disodium (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-[(3-carboxylatopropanoyl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate
Molecular Formula
C34H48Na2O7
InChI Key
BQENDLAVTKRQMS-SBBGFIFASA-L
SMILES
[Na+].[Na+].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CCC([O-])=O)C(C)(C)[C@]3([H])CC[C@@]12C)C([O-])=O
Appearance (Color)
White to pale cream
Assay from Supplier's CofA
≥97.0%
Form
Powder

Description

Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water to 100 mM.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.
RUO – Research Use Only

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