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Ampicillin sodium salt, Thermo Scientific Chemicals
Catalog number: J63807.06
5 g, Each
Thermo Scientific™
Ampicillin sodium salt, Thermo Scientific Chemicals
Catalog number: J63807.06
5 g, Each
Quantity
Catalog number: J63807.06
also known as J63807-06
Price (USD)
Special offer:
60.65 71.30 Save 10.65 (14%)
Ends: 15-Oct-2024
Each
Quantity
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Chemical Identifiers
CAS
69-52-3
IUPAC Name
sodium (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Molecular Formula
C16H18N3NaO4S
InChI Key
KLOHDWPABZXLGI-YWUHCJSESA-M
SMILES
[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O
Specifications
Specification SheetAppearance (Color)
White to pale cream
Form
Powder or crystals or crystalline powder
Assay from Suppliers CofA
Potency (Anhydrous): ≥845 µg/mg
pH
8.0-10.0 (1% solution in water)
Solution Test
Soluble (50 mg/ml in water)
Description
Ampicillin sodium salt is a reagent for transformed cells expressing beta-lactamase. It acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Ampicillin sodium salt is a semi-synthetic derivative of penicillin with a broad-spectrum antibacterial activity against several species, including Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Ralstonia solanacearum
• It can inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins, inhibiting peptidoglycan synthesis, which is an essential component of the bacterial cell wall
Application
• Ampicillin sodium salt has been used as a reagent for transformed cells that express β-lactamase
• It can be used to select for ampicillin resistance in mutated and transformed cells
• Ampicillin sodium salt acts as a structural analog of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme preventing the cross-linking of the cell wall peptidoglycan, which is necessary for the growth of the bacterium
RUO – Research Use Only
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