Thermo Scientific Chemicals

Dizocilpine maleate, 99+%, Thermo Scientific Chemicals

Catalog number: J63917.MA
10 mg, Each
Thermo Scientific Chemicals

Dizocilpine maleate, 99+%, Thermo Scientific Chemicals

Catalog number: J63917.MA
10 mg, Each
Quantity
Catalog number: J63917.MA
also known as J63917-MA
Price (USD)
Quantity
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Chemical Identifiers

CAS
77086-22-7
IUPAC Name
(1S,9R)-1-methyl-16-azatetracyclo[7.6.1.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,10,12,14-hexaene; (2Z)-but-2-enedioic acid
Molecular Formula
C20H19NO4
InChI Key
QLTXKCWMEZIHBJ-PJGJYSAQSA-N
SMILES
OC(=O)C=C/C(O)=O.C[C@]12N[C@H](CC3=CC=CC=C13)C1=CC=CC=C21
Form
Powder or crystals or crystalline powder
Proton NMR
Conforms
Purity
≥99.0%

Description

Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

Solubility
Soluble in ethanol.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
RUO – Research Use Only

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