Imiquimod is a caspase 3 activator which acts as an immunomodulator and displays antiviral and anti-tumor activity. It is a patient-applied cream used for the treatment of genital warts and basal cell carcinoma. It is also used to cure actinic keratosis on the face and scalp. It belongs to a group of drugs called immune response modifiers, which work by activating the immune system to fight abnormal skin growth.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide. Slightly soluble in water. Insoluble in ethanol.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
Arits, A., Nelemans, P.; Smeets, N. K. Response to ‘Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial: a critical appraisal’. Br. J. Dermatol. 2015, 172 (1), 11-12.
Kono, T.; Biswas, G.; Fall, J.; Mekata, T.; Hikima, J. I.; Itami, T.; Sakai, M. Adjuvant effects of poly I: C and imiquimod on the immunization of kuruma shrimp (Marsupenaeus japonicus) with a recombinant protein, VP28 against white spot syndrome virus. Aquaculture 2015, 446, 236-241.