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Cytidine-5'-diphosphocholine sodium salt
Intermediate in the synthesis of phosphatidylcholine; also a phospholipase inhibitor
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Catalog number J64161.14
also known as J64161-14
Price (USD)/ Each
141.00
-
Quantity:
25 g
Price (USD)/ Each
141.00
Cytidine-5'-diphosphocholine sodium salt
Catalog numberJ64161.14
Price (USD)/ Each
141.00
-
Chemical Identifiers
CAS33818-15-4
IUPAC Namesodium 2-(trimethylazaniumyl)ethyl ({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
Molecular FormulaC14H25N4NaO11P2
InChI KeyYWAFNFGRBBBSPD-OCMLZEEQSA-M
SMILES[Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(N)=NC1=O
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Specifications
Specification Sheet
Specification SheetAssay (HPLC)95.0% min.
Assay (unspecified)Solubility: 5% w/v in water
Loss on Drying6.0% max.
Cytidine-5'-diphosphocholine sodium salt hydrate acts as a neuroprotective agent in situations of hypoxia and ischemia. It is used as biosynthetic intermediate of membrane phospholipids. It is a cerebral vasodilator and inhibits PLA2 activation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cytidine-5′-diphosphocholine sodium salt hydrate acts as a neuroprotective agent in situations of hypoxia and ischemia. It is used as biosynthetic intermediate of membrane phospholipids. It is a cerebral vasodilator and inhibits PLA2 activation.
Solubility
Soluble in water (100 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Cytidine-5′-diphosphocholine sodium salt hydrate acts as a neuroprotective agent in situations of hypoxia and ischemia. It is used as biosynthetic intermediate of membrane phospholipids. It is a cerebral vasodilator and inhibits PLA2 activation.
Solubility
Soluble in water (100 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- W.M.Clark; S.J.Warach; L.C.Pettigrew; R.E.Gammans; L.A.Sabounjian. A randomized dose-response trial of citicoline in acute ischemic stroke patients. Citicoline Stroke Study Group. Neurology. 1997, 49,(3), 671-678.
- S.Warach, MD, PhD; L.Creed Pettigrew, MD; J.F.Dashe, MD, PhD; P.Pullicino MD; David M.Lefkowitz, MD; L.Sabounjian, RN; K.Harnett, MS; U.Schwiderski, PhD; R.Gammans, PhD. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Annals of Neurology. 2000, 48,(5), 713-722.