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Guanidine thiocyanate, Molecular Biology Grade
Catalog number: J65104.36
500 g, Each
Thermo Scientific Chemicals
Guanidine thiocyanate, Molecular Biology Grade
Catalog number: J65104.36
500 g, Each
Quantity
Catalog number: J65104.36
also known as J65104-36
Price (USD)
Special offer:
314.65 333.65 Online priceSave 19.00 (5%)
Ends: 15-Oct-2024
Each
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Chemical Identifiers
CAS
593-84-0
IUPAC Name
guanidine; sulfanylformonitrile
Molecular Formula
C2H6N4S
InChI Key
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
SMILES
SC#N.NC(N)=N
Specifications
Specification SheetAppearance (Color)
White to pale yellow
Form
Crystalline powder
Assay from Supplier's CofA
≥99.0% (TItration)
DNase
None detected
RNase
None detected
Description
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
Solubility
Soluble in water (1420 g/L) at 20°C, and ethanol (5%).
Notes
Light Sensitive. Keep container tightly closed. Store away from oxidizing agents.
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.
Solubility
Soluble in water (1420 g/L) at 20°C, and ethanol (5%).
Notes
Light Sensitive. Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only
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