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Cefoperazone sodium salt, Thermo Scientific Chemicals
Catalog number: J65185.06
5 g, Each
Thermo Scientific Chemicals
Cefoperazone sodium salt, Thermo Scientific Chemicals
Catalog number: J65185.06
5 g, Each
Quantity
Catalog number: J65185.06
also known as J65185-06
Price (USD)
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218.65 257.00 Save 38.35 (14%)
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Chemical Identifiers
CAS
62893-20-3
IUPAC Name
sodium (6R,7R)-7-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido]-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Molecular Formula
C25H26N9NaO8S2
InChI Key
NCFTXMQPRQZFMZ-WERGMSTESA-M
SMILES
[Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSC4=NN=NN4C)=C(N3C2=O)C([O-])=O)C2=CC=C(O)C=C2)C(=O)C1=O
Specifications
Specification SheetComment
Crystallinity: Conforms to standard
Water Content (Karl Fischer Titration)
≤ 5.0%
pH
4.5 to 6.5 (0.1% solution in room temperature)
Appearance (Color)
White to pale cream
Form
Crystalline powder
Description
For studying the expression, binding, and inhibition of penicillin-binding proteins.Cefoperazone sodium salt is used in the study of drug-protein binding, expression and inhibition of penicillin-binding proteins during cell wall synthesis. It is as an antibacterial and antimicrobial agent useful for prevention of postoperative infection. It is used as an inhibitor of inactivation of alfa-antitrypsin.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Cefoperazone sodium salt is a semi-synthetic, broad-spectrum, third-generation cephalosporin compound with antibiotic and bactericidal activities
• This compound can inhibit bacterial cell wall synthesis by inactivating penicillin-binding proteins and consequently interfering with the final transpeptidation step required for cross-linking peptidoglycan units, an important component of bacterial cell walls. This leads to a reduction in cell wall stability, causing cell lysis
Application
• Cefoperazone sodium salt exhibits activity against β-lactamase resistant microorganisms
• This compound is also used for studying the expression, binding, and inhibition of penicillin-binding proteins
• Cefoperazone is active in vitro against most gram-positive and gram-negative bacteria, including β-lactamase strains
• This compound has the ability to inhibit ∝-antitrypsin
RUO – Research Use Only
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