ANS forms an inclusion complex with cyclodextrin. Such model systems are useful to mimic biological recognition and can be studied by measuring the change in fluorescence of free-ANS to complexed-ANS. When ANS enters the hydrophobic core of cyclodestrin, it’s fluorescence increases. It is commonly used to study molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
ANS forms an inclusion complex with cyclodextrin. Such model systems are useful to mimic biological recognition and can be studied by measuring the change in fluorescence of free-ANS to complexed-ANS. When ANS enters the hydrophobic core of cyclodestrin, it’s fluorescence increases. It is commonly used to study molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media.
Solubility
Soluble in water, 1N NaOH, and methanol.
Notes
Light & Air Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
Neha Jain.; Mily Bhattacharya.; Samrat Mukhopadhyay. Kinetics of Surfactant-induced Aggregation of Lysozyme Studied by Fluorescence Spectroscopy. Journal of Fluorescence. 2011, 21, (2), 615-625.