Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.
Solubility
Soluble in water
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
Robert R. Chauvette.; Edwin H. Flynn. Chemistry of Cephalosporin Antibiotics. V.1 Amides and Esters of Cephalothin2. J. Med. Chem. 1966, 9, (5), 741-745.
Murillo, J.A.; Lemus, J.M.; Garcia, L.F. Resolution of binary mixtures of cephalothin and clavulanic acid by using first derivative spectrophotometry. Fresenius’ Journal of Analytical Chemistry. 1994, 349, (10), 761-767.