Thermo Scientific Chemicals

DAPT, Thermo Scientific Chemicals

Catalog number: J65864.MA
10 mg, Each
Thermo Scientific Chemicals

DAPT, Thermo Scientific Chemicals

Catalog number: J65864.MA
10 mg, Each
Quantity
Catalog number: J65864.MA
also known as J65864-MA
Price (USD)
Quantity
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Chemical Identifiers

CAS
208255-80-5
IUPAC Name
tert-butyl 2-{2-[2-(3,5-difluorophenyl)acetamido]propanamido}-2-phenylacetate
Molecular Formula
C23H26F2N2O4
InChI Key
DWJXYEABWRJFSP-UHFFFAOYNA-N
SMILES
CC(NC(=O)CC1=CC(F)=CC(F)=C1)C(=O)NC(C(=O)OC(C)(C)C)C1=CC=CC=C1
Form
Solid
Assay (HPLC)
95.0% min.
Appearance (Color)
White

Description

DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth,
RUO – Research Use Only

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