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Apramycin sulfate, Thermo Scientific Chemicals
Catalog number: J66616.09
10 g, Each
Thermo Scientific Chemicals
Apramycin sulfate, Thermo Scientific Chemicals
Catalog number: J66616.09
10 g, Each
Quantity
Catalog number: J66616.09
also known as J66616-09
Price (USD)
280.00
Each
Quantity
-
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Chemical Identifiers
CAS
65710-07-8
IUPAC Name
(2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
Molecular Formula
C21H43N5O15S
InChI Key
WGLYHYWDYPSNPF-RQFIXDHTSA-N
SMILES
OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]1O[C@H](CO)[C@@H](N)[C@H](O)[C@H]1O
Specifications
Specification SheetLoss on Drying
≤ 14%
Appearance (Color)
Pale yellow to yellow-brown powder
Potency
≥ 550 µg/mg (calculated on dry basis)
Form
Powder
Description
Apramycin sulfate binds to the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Apramycin is a 2-deoxysteptamine derivative and an aminoglycoside originally isolated from Streptomyces tenebrarius
• Apramycin sulfate is comprised of a bicyclic sugar moiety and a monosubstituted deoxystreptamine attached to a sulfate group
Application
• Apramycin sulfate exhibits antibiotic activity against gram-negative bacteria
• It is suitable for laboratory use against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa
• It is also used for laboratory study of infectious disease
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
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