N,N'-Methylenebisacrylamide is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins. It has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N,N′-Methylenebisacrylamide is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins. It has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.
Solubility
Soluble in water or methanol
Notes
Air & Light Sensitive. Store in the dark. Store under dry inert gas. Incompatible with light, heat, air and oxidizing agents. Store at 4°C.
RUO – Research Use Only
Timothy Olding; Oliver Holmes; Paul Dejean; Kim B McAuley; Ken Nkongchu; Giles Santyr; L John Schreiner. Small field dose delivery evaluations using cone beam optical computed tomography-based polymer gel dosimetry. Journal of Medical Physics.2011, 36, (1), 3-14.
Carl Julien; Alexis Bretteville; Emmanuel Planel. Biochemical isolation of insoluble tau in transgenic mouse models of tauopathies. Methods in Molecular Biology.2012, 849, 473-491.