Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Albumin is derived from human serum
• Albumin is affected by oxidative stress that can alter its redox state and thereby alter its physiological function
Application
• Albumin has been used in the preparation of nanocarriers as advanced drug delivery systems
• It has the ability to facilitate diffusion and active transport of substances such as steroids, fatty acids, and thyroid hormones
• It also helps maintain the colloidal osmotic pressures of blood and buffers pH
• It can bind to some substances, including drugs such as ibuprofen and warfarin, and strongly influence their pharmacokinetics
• It is involved in the formulation of media for culture of mammalian cells for laboratory research
Literature References
H.S. Stern, I. Zolle; J.G. McAfee. Preparation of technetium (Tc99m)-labeled serum albumin (human). The International Journal of Applied Radiation and Isotopes. 1965, 16 (4), 283-288. H. Zia.; J. C. Price. Binding study of tetracyclines to human serum albumin using difference spectrophotometry. J. Pharm. Sci. 1976, 65 (2), 226-230.
Karimi M, Bahrami S, Ravari SB, Zangabad PS, Mirshekari H, Bozorgomid M, Shahreza S, Sori M, Hamblin MR. Albumin nanostructures as advanced drug delivery systems. Expert Opin Drug Deliv. 2016, 13, (11), 1609-1623. Francis GL. Albumin and mammalian cell culture: implications for biotechnology applications. Cytotechnology. 2010, 62, (1), 1-16.