Carbenicillin disodium salt, 50 mg/ml in distilled water, sterile-filtered
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Carbenicillin disodium salt, 50 mg/ml in distilled water, sterile-filtered
Thermo Scientific Chemicals

Carbenicillin disodium salt, 50 mg/ml in distilled water, sterile-filtered

Carbenicillin disodium salt, CAS # 4800-94-6, is the disodium salt form of carbenicillin, a semisynthetic compound with broad-spectrum antibacterial and β-lactamase-resistant activities.
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Catalog number J67159.AD
also known as J67159-AD
Price (USD)/ Each
267.65
Online exclusive
297.00 
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Quantity:
50 mL
Request bulk or custom format
Price (USD)/ Each
267.65
Online exclusive
297.00 
Save 29.35 (10%)
Add to cart
Carbenicillin disodium salt, 50 mg/ml in distilled water, sterile-filtered
Catalog numberJ67159.AD
Price (USD)/ Each
267.65
Online exclusive
297.00 
Save 29.35 (10%)
-
Add to cart
Chemical Identifiers
CAS4800-94-6
IUPAC Namedisodium (2S,5R,6R)-6-(2-carboxylato-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Molecular FormulaC17H16N2Na2O6S
InChI KeyRTYJTGSCYUUYAL-YCAHSCEMSA-L
SMILES[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Appearance (Color)Clear colorless to light yellow
CommentComponent is dissolved in UV treated 18.2 megohm-cm ± 1 water, followed by pH adjustment and filtered through 0.22 micron filter.
Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis. Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin, Antimicrobial spectrum.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Carbenicillin disodium salt is a semisynthetic compound with antibacterial and β-lactamase-resistant activities and is effective against gram-negative bacteria
• In in vitro studies, carbenicillin disodium salt can totally suppress the proliferation of Agrobacterium
Application
• Due to its antibacterial activity this compound can be used to control bacterial cell wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. This can lead to incomplete bacterial cell wall synthesis to eventually cause cell lysis
• It has also been used in studies to evaluate the role of penicillin-sensitive transpeptidases in cell wall biosynthesis
RUO – Research Use Only

General References:

  1. Cole, M. R.; Hobden, J. A.; Warner, I. M. Recycling Antibiotics into GUMBOS: A New Combination Strategy to Combat Multi-Drug-Resistant Bacteria. Molecules 2015, 20 (4), 6466-6487.
  2. Sonopo, M. S.; Venter, K.; Boyle, G.; Winks, S.; Painter, B. M.; Zeevaart, J. R. Carbon-14 radiolabeling and in vivo biodistribution of a potential anti-TB compound. J. Labelled Comp. Radiopharm. 2015, 58 (2), 23-29.