Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered
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Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered
Thermo Scientific Chemicals

Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered

Blasticidin S hydrochloride, CAS # 3513-03-9, is an antibiotic isolated from Streptomyces griseochromogenes that inhibits peptide bond formation by ribosome.
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Catalog number J67216.8EQ
also known as J67216-8=
Price (USD)/ Each
376.00
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Quantity:
5 x 1 mL
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Price (USD)/ Each
376.00
Add to cart
Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered
Catalog numberJ67216.8EQ
Price (USD)/ Each
376.00
-
Add to cart
Chemical Identifiers
CAS3513-03-9
IUPAC Name6-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-[3-amino-5-(N-methylcarbamimidamido)pentanamido]-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride
Molecular FormulaC17H27ClN8O5
InChI KeyYQXYQOXRCNEATG-UHFFFAOYNA-N
SMILESCl.CN(CCC(N)CC(=O)NC1C=CC(OC1C(O)=O)N1C=CC(N)=NC1=O)C(N)=N
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Assay (special)Bacterial endotoxin: ≤ 1.0 EU/mg
Appearance (Color)Clear colorless to pale cream
Assay (HPLC)≥ 95%
pH7.1 to 7.5
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Blasticidin S hydrochloride, acts quickly by inhibiting peptide bond formation by the ribosome. The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative. Blasticidin S is used for the prevention of contamination of cell cultures.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Blasticidin S hydrochloride is an antibiotic that works by inhibiting peptide bond formation by the ribosome

Application

• Blasticidin S hydrochloride is a nucleoside antibiotic that inhibits protein synthesis in prokaryotic and eukaryotic cells
• It inhibits peptide bond formation by the ribosome

RUO – Research Use Only

General References:

  1. Masanori Sugiyama; Akinori Takeda; Soon-Young Paik; Osamu Nimi; Ryosaku Nomi. Acetylation Of Blasticidin S By Its Producing Actinomycetes. The Journal of Antibiotics. 1986, 39 (6), 827-832.