Thermo Scientific Chemicals

Trimethylsilyl azide, 94%, Thermo Scientific Chemicals

Catalog number: L00173.06
5 g, Each
Thermo Scientific Chemicals

Trimethylsilyl azide, 94%, Thermo Scientific Chemicals

Catalog number: L00173.06
5 g, Each
Quantity
Catalog number: L00173.06
also known as L00173-06
Price (USD)
Quantity
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Chemical Identifiers

CAS
4648-54-8
Form
Liquid
Comment
Specification differs for U.S. and non-U.S. material where indicated
Appearance (Color)
Clear to slightly hazy colorless to pale pink
Refractive Index
1.4110-1.4180 @ 20°C (non-U.S. specification)
Assay (GC)
≥92.0%

Description

Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.

Solubility
Miscible with toluene, dichloromethane, diethyl ether and most organic solvents.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only

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