4-Bromobenzeneboronic acid, 97+%, Thermo Scientific Chemicals
4-Bromobenzeneboronic acid, 97+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4-Bromobenzeneboronic acid, 97+%, Thermo Scientific Chemicals

Have Questions?
Change viewbuttonViewtableView
Quantity:
1 g
5 g
25 g
Catalog number L01565.03
also known as L01565-03
Price (USD)/ Each
24.70
-
Add to cart
Quantity:
1 g
Request bulk or custom format
Price (USD)/ Each
24.70
Add to cart
4-Bromobenzeneboronic acid, 97+%, Thermo Scientific Chemicals
Catalog numberL01565.03
Price (USD)/ Each
24.70
-
Add to cart
Chemical Identifiers
CAS5467-74-3
IUPAC Name(4-bromophenyl)boronic acid
Molecular FormulaC6H6BBrO2
InChI KeyQBLFZIBJXUQVRF-UHFFFAOYSA-N
SMILESOB(O)C1=CC=C(Br)C=C1
View more
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to cream to pale brown
Assay (HPLC)≥97.0%
FormCrystals or powder or crystalline powder or lumps or fused solid or flakes or granules
Assay (Aqueous acid-base Titration)≥97.0%
Identification (FTIR)Conforms
View more
4-Bromobenzeneboronic acid is a reagent used for Palladium catalyzed Suzuki-Miyaura cross-couplings, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. It is also used in the preparation of Protein modulators and enzymatic and kinase inhibitors, Gallate-based obovatol analogs with potential anti-tumor activity. It is used as a reagent for Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes, Copper-catalyzed cross-couplings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Bromobenzeneboronic acid is a reagent used for Palladium catalyzed Suzuki-Miyaura cross-couplings, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. It is also used in the preparation of Protein modulators and enzymatic and kinase inhibitors, Gallate-based obovatol analogs with potential anti-tumor activity. It is used as a reagent for Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes, Copper-catalyzed cross-couplings.

Solubility
Soluble in methanol. Insoluble in water.

Notes
Store in a cool and dark place. Store away from incompatible materials such as oxidizing agents. Incompatible with Oxidizing agents, Acids, Bases, Alcohols
RUO – Research Use Only

General References:

  1. GC reagent for diols: J. Chromat., 158, 33 (1978); 186, 307 (1979).
  2. Carbonylative cross-coupling with iodobenzenes and CO, catalyzed by trans-Dichlorobis(triphenyl phosphine) palladium(II) , 10491, gives unsymmetrical diaryl ketones: Tetrahedron Lett., 34, 7595 (1993); J. Org. Chem., 63, 4726 (1998). For reactions of boronic acids, see Appendix 5.