Diphenylacetonitrile undergoes anhydrous condensation with ethyl-4-bromo-butyrate. This is followed by its hydrolysis in alkaline medium that is used in the quantitative determination of 3-cyano-3,3-diphenylpropionic acid.
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Applications
Diphenylacetonitrile undergoes anhydrous condensation with ethyl-4-bromo-butyrate. This is followed by its hydrolysis in alkaline medium that is used in the quantitative determination of 3-cyano-3,3-diphenylpropionic acid.
Solubility
Insoluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Everett M. Schultz.; Charles M. Robb.; James M. Sprague. The Reaction of 1-Dimethylamino-2-chloropropane with Diphenylacetonitrile. The Structure of Amidone. J. Am. Chem. Soc. 1947, 69 (10), 2454-2459.
- Wm. Bradley ReidJr.; James H. Hunter. Preparation of Diphenylacetonitrile. J. Am. Chem. Soc. 1948, 70(10), 3515-3515.