2-Iodo-2-methylpropane is used as a chemical reagent in organic synthesis. Further, it serves as a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Iodo-2-methylpropane is used as a chemical reagent in organic synthesis. Further, it serves as a pharmaceutical intermediate.
Solubility
Miscible with ethanol and ether.
Notes
Light sensitive. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
With DMSO, generates iodomethylsulfonium iodide, a reagent which is more reactive than that derived from tert-Butyl bromide, A13727 for the cleavage of ethylene thioacetals.
Fujii, S.; Nakano, M.; Yamaoka, Y.; Takasu, K.; Yamada, K. I.; Tomioka, K. Contiguous radical pivaloyloxymethylation-directed C(sp3)-H iodination of N-tosyl cycloalkanecarbaldimine. Tetrahedron Lett. 2015, 56 (23), 3086-3089.
Ma, G.; Fujita, T.; Sibi, M. P. Lewis acid mediated diastereoselective intermolecular radical addition/trapping with pyrazolidinone acrylimides. Tetrahedron Lett. 2015, 56 (23), 3571-3574.