4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.
Solubility
Soluble in water.
Notes
Incompatible with bases, amines and oxidizing agents.
RUO – Research Use Only
General References:
- Eyley, S.; Vandamme, D.; Lama, S.; Van den Mooter, G.; Muylaert, K.; Thielemans, W. CO2 controlled flocculation of microalgae using pH responsive cellulose nanocrystals. Nanoscale 2015, 7 (34), 14413-14421.
- Paraskevopoulos, G.; Alivertis, D.; Theodorou, V.; Skobridis, K. New Calix[4]arene-Cored Peripherally Functionalized Dendrimers: Synthesis and Conformational Characteristics. Helv. Chim. Acta 2015, 98 (5), 593-603.