Thermo Scientific Chemicals

Triethyl orthopropionate, 98%, Thermo Scientific Chemicals

Catalog number: L08172.AE
100 mL, Each
Thermo Scientific Chemicals

Triethyl orthopropionate, 98%, Thermo Scientific Chemicals

Catalog number: L08172.AE
100 mL, Each
Quantity
Catalog number: L08172.AE
also known as L08172-AE
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Chemical Identifiers

CAS
115-80-0
IUPAC Name
1,1,1-triethoxypropane
Molecular Formula
C9H20O3
InChI Key
FGWYWKIOMUZSQF-UHFFFAOYSA-N
SMILES
CCOC(CC)(OCC)OCC
Appearance (Color)
Clear colorless
Refractive Index
1.4000-1.4040 @ 20?C
Form
Liquid
Assay (GC)
≥97.5%

Description

Used as intermediates in pharmaceutical chemical and organic synthesize. It can react with N-benzoyl-glycine in the presence of 4-(dimethylamino)pyridine and acetic anhydride to produce 4-(1-ethoxy-propylidene)-2-phenyl-4H-oxazol-5-one. It is also applied as a starting material in the synthesis of Triethyl orthoacrylate. Triethyl orthopropionate is also commonly used in Claisen rearrangement reactions that yield γ,δ-unsaturated esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as intermediates in pharmaceutical chemical and organic synthesize. It can react with N-benzoyl-glycine in the presence of 4-(dimethylamino)pyridine and acetic anhydride to produce 4-(1-ethoxy-propylidene)-2-phenyl-4H-oxazol-5-one. It is also applied as a starting material in the synthesis of Triethyl orthoacrylate. Triethyl orthopropionate is also commonly used in Claisen rearrangement reactions that yield γ,δ-unsaturated esters.

Solubility
Hydrolyzes slowly in water. Soluble in alcohol, chloroform, ethyl acetate and ether.

Notes
Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect against electrostatic charges. Keep ignition sources away.
RUO – Research Use Only

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