1,4-Bis(trimethylsilyl)-1,3-butadiyne is used in Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s. It is also used as pharmaceutical intermediates.
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Applications
1,4-Bis(trimethylsilyl)-1,3-butadiyne is used in Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s. It is also used as pharmaceutical intermediates.
Solubility
Insoluble in water.
Notes
Store at 4°C. Incompatible materials are Strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only
Tobias N Hoheisel; Holger Frauenrath. A convenient Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s.Organic Letters.2008, 10 (20), 4525-4528.
Tetsuo Kusumoto; Tamejiro Hiyama. Hydrosilylation of 1,4-Bis(Trimethylsilyl)-1,3-Butadiyne. Chemistry Letters.1985, 14 (9), 1405-1408.