Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.
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Applications
Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.
Solubility
Fully miscible in water.
Notes
Store in cool dry condition. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Ioannis N. Houpis.; Lawrence E. Patterson.; Charles A. Alt.; John R. Rizzo.; Tony Y. Zhang.; Michael Haurez. Synthesis of PPAR Agonist via Asymmetric Hydrogenation of a Cinnamic Acid Derivative and Stereospecific Displacement of (S)-2-Chloropropionic Acid.Org. Lett. 2005, 7 (10),1947-1950 .
- Atsushi Kurata.; Tatsuo Kurihara.; Harumi Kamachi.; Nobuyoshi Esaki. Asymmetric reduction of 2-chloroacrylic acid to (S)-2-chloropropionic acid by a novel reductase from Burkholderia sp. WSTetrahedron: Asymmetry. 2004, 15 (18),2837-2839 .