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Dibenzyl phosphite, 90+%, Thermo Scientific Chemicals
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Catalog number L09858.22
also known as L09858-22
Price (USD)/ Each
320.00
-
Quantity:
100 g
Price (USD)/ Each
320.00
Dibenzyl phosphite, 90+%, Thermo Scientific Chemicals
Catalog numberL09858.22
Price (USD)/ Each
320.00
-
Chemical Identifiers
CAS17176-77-1
IUPAC Namebis(benzyloxy)(oxo)-λ⁵-phosphanylium
Molecular FormulaC14H14O3P
InChI KeyRQKYHDHLEMEVDR-UHFFFAOYSA-N
SMILESO=[P+](OCC1=CC=CC=C1)OCC1=CC=CC=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to yellow
Assay by NMR≥90%
Refractive Index1.5500-1.5580 @ 20?C
FormLiquid
Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.
Solubility
Soluble in DMSO, Methanol. Reacts with water.
Notes
Store at 4°C. Moisture Sensitive. Incompatible with moisture and oxidizing agents. Store under dry inert gas. Store away from oxidizing agents.
Dibenzyl phosphite is used for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate. It is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.
Solubility
Soluble in DMSO, Methanol. Reacts with water.
Notes
Store at 4°C. Moisture Sensitive. Incompatible with moisture and oxidizing agents. Store under dry inert gas. Store away from oxidizing agents.
RUO – Research Use Only
General References:
- Lee J. Silverberg; John L. Dillon; Purushotham Vemishetti. A simple, rapid and efficient protocol for the selective phosphorylation of phenols with dibenzyl phosphite.Tetrahedron Letters.1996, 37 771-774.
- Yu-Pei Cheng; Hui-Ting Chen; Chun-Cheng Lin. A convenient and highly stereoselective approach for α-galactosylation performed by galactopyranosyl dibenzyl phosphite with remote participating groups.Tetrahedron Letters.2002, 43 7721-7723.
- A selective method for the phosphorylation of phenols involves reaction in the presence of N-ethyldiisopropylamine and DMAP to give the dibenzyl phenyl phosphate: Tetrahedron Lett., 37, 771 (1996).