Ethyl isocyanatoacetate, 98%, Thermo Scientific Chemicals
Ethyl isocyanatoacetate, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ethyl isocyanatoacetate, 98%, Thermo Scientific Chemicals

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Quantity:
25 g
1 g
5 g
Catalog number L10609.14
also known as L10609-14
Price (USD)/ Each
232.00
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Quantity:
25 g
Request bulk or custom format
Price (USD)/ Each
232.00
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Ethyl isocyanatoacetate, 98%, Thermo Scientific Chemicals
Catalog numberL10609.14
Price (USD)/ Each
232.00
-
Add to cart
Chemical Identifiers
CAS2949-22-6
IUPAC Nameethyl 2-isocyanatoacetate
Molecular FormulaC5H7NO3
InChI KeyDUVOZUPPHBRJJO-UHFFFAOYSA-N
SMILESCCOC(=O)CN=C=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to pale yellow
FormLiquid
Assay (GC)>97.5%
Refractive Index1.4220-1.4260 @ 20?C
6-(carboxymethylureido)-(±)-nicotine (CMUNic)was prepared by using ethyl isocyanatoacetate. Ethyl isocyanatoacetate has been used in the preparation of nicotine immunogen, ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate, imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-(carboxymethylureido)-(±)-nicotine (CMUNic)was prepared by using ethyl isocyanatoacetate. Ethyl isocyanatoacetate has been used in the preparation of nicotine immunogen, ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate, imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione.

Solubility
Reacts with water.

Notes
Moisture Sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from moisture, water, heat.
RUO – Research Use Only

General References:

  1. Y Hieda et. al. Active immunization alters the plasma nicotine concentration in rats. Journal of Pharmacology and Experimental Therapeutics. 1997, 283, (3), 1076-1081.
  2. Malcolm FG. Antitumour imidazotetrazines. Part 33. New syntheses of the antitumour drug temozolomide using 'masked'methyl isocyanates. J. Chem. Soc. Perkin Trans. 1995, 121 2783-87.