2-Fluoro-1-methylpyridinium p-toluenesulfonate Is a peptide coupling reagent. Also used in the synthesis of ? -ribonucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Fluoro-1-methylpyridinium p-toluenesulfonate Is a peptide coupling reagent. Also used in the synthesis of ɑ -ribonucleotides.
Solubility
Soluble in water (hydrolyzes), DMSO, dichloromethane, and acetonitrile.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Peter G. Odell; Richard P. N. Veregin; Lora M. Michalak; and Michael K. Characteristics of the Stable Free Radical Polymerization of Styrene in the Presence of 2-Fluoro-1-methylpyridinium p-Toluenesulfonate. Macromolecules. 1997, 30, (8), 2232-2237.
- J. Martin E. Quirke; Christopher L. Adams; Gary J. Van Berkel. Chemical Derivatization for Electrospray Ionization Mass Spectrometry. 1. Alkyl Halides, Alcohols, Phenols, Thiols, and Amines. Anal. Chem. 1994, 66, (8), 1302-1315.
- Peptide coupling reagent. For peptide reagents, see Appendix 6. Also used in the synthesis of ɑ -ribonucleotides: Chem. Lett., 547 (1984).
- Review of synthetic reactions of onium salts of aza-arenes: Angew. Chem. Int. Ed., 18, 707 (1979).