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1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 97%, Thermo Scientific Chemicals
Catalog number: L11171.14
25 g, Each
Thermo Scientific Chemicals
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 97%, Thermo Scientific Chemicals
Catalog number: L11171.14
25 g, Each
Quantity
Catalog number: L11171.14
also known as L11171-14
Price (USD)
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572.65 674.00 Save 101.35 (15%)
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Chemical Identifiers
CAS
69304-37-6
IUPAC Name
chloro({[chlorobis(propan-2-yl)silyl]oxy})bis(propan-2-yl)silane
Molecular Formula
C12H28Cl2OSi2
InChI Key
DDYAZDRFUVZBMM-UHFFFAOYSA-N
SMILES
CC(C)[Si](Cl)(O[Si](Cl)(C(C)C)C(C)C)C(C)C
Specifications
Specification SheetAppearance (Color)
Clear colorless to pale yellow
Form
Liquid
Assay (GC)
≥96.0%
Identification (FTIR)
Conforms
Refractive Index
1.4525-1.4575 @ 20?C
Description
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3'- and 5'-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3′- and 5′-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.
Solubility
Miscible with dimethylformamide, hexane, ethyl acetate, chloroform and dichloromethane.
Notes
Incompatible with strong oxidizing agents and water.
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3′- and 5′-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.
Solubility
Miscible with dimethylformamide, hexane, ethyl acetate, chloroform and dichloromethane.
Notes
Incompatible with strong oxidizing agents and water.
RUO – Research Use Only
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