Sorbitan monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. It is used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It is also used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Sorbitan monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. It is used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It is also used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.
Solubility
Soluble in 2-ethoxyethanol, ethanol and methanol. Not miscible or difficult to mix in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
Claire Berton.; Claude Genot.; Dominique Guibert.; Marie-Hélène Ropers.; Claire Berton.; Claude Genot, Dominique Guibert.; Marie-Hélène Ropers. Effect of lateral heterogeneity in mixed surfactant-stabilized interfaces on the oxidation of unsaturated lipids in oil-in-water emulsions. Journal of Colloid and Interface Science. 2012, 377 (1), 244-250.
Young Keun Choi.; Bijay K. Poudel.; Nirmal Marasini.; Kwan Yeol Yang.; Jeong Whan Kim.; Jong Oh Kim.; Han-Gon Choi.; Chul Soon Yong. Enhanced solubility and oral bioavailability of itraconazole by combining membrane emulsification and spray drying technique. International Journal of Pharmaceutics. 2012, 434 (1-2), 264-271.
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Nonionic surfactant.