4,5-Dicyanoimidazole, 98+%, Thermo Scientific Chemicals
4,5-Dicyanoimidazole, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4,5-Dicyanoimidazole, 98+%, Thermo Scientific Chemicals

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Quantity:
5 g
25 g
Catalog number L12215.06
also known as L12215-06
Price (USD)/ Each
31.65
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Ends: 31-Dec-2024
36.70 
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Quantity:
5 g
Request bulk or custom format
Price (USD)/ Each
31.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
36.70 
Save 5.05 (14%)
Add to cart
4,5-Dicyanoimidazole, 98+%, Thermo Scientific Chemicals
Catalog numberL12215.06
Price (USD)/ Each
31.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
36.70 
Save 5.05 (14%)
-
Add to cart
Chemical Identifiers
CAS1122-28-7
IUPAC Name1H-imidazole-4,5-dicarbonitrile
Molecular FormulaC5H2N4
InChI KeyXGDRLCRGKUCBQL-UHFFFAOYSA-N
SMILESN#CC1=C(N=CN1)C#N
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SpecificationsSpecification SheetSpecification Sheet
Assay from Suppliers CofA≥97.5% (U.S. specification)
Appearance (Color)White to cream to dark brown to pale brown
FormCrystals or powder or crystalline powder or fused solid
Assay (HPLC)≥97.5% (non-U.S. specification)
CommentSpecification differs for U.S. and non-U.S. material where indicated
4,5-Dicyanoimidazole is used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. It is often used as an alternative to tetrazole.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4,5-Dicyanoimidazole is used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. It is often used as an alternative to tetrazole.

Solubility
Soluble in Acetonitrile: 1.8g/10ml, DMSO, Methanol.

Notes
Store in a cool, dry conditions in well sealed container. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Chandra Vargeese; Jeff Carter; John Yegge; Shira Krivjansky; Alecia Settle; Eric Kropp; Kent Peterson and Wolfgang Pieken. Efficient activation of nucleoside phosphoramidites with 4,5-dicyanoimidazole during oligonucleotide synthesis. Nucl. Acids Res.1998, 26, (4), 1046-1050.
  2. Paul G. Apen; Paul G. Rasmussen. Synthesis and properties of new derivatives of 4,5-dicyanoimidazole and 4,4',5,5'-tetracyano-2,2'-biimidazole. J. Am. Chem. Soc.1991, 113, (16), 6178-6187.