4-(Trifluoromethyl)phenyl isocyanate has been used in the synthesis of fluorescent photoinduced electron transfer (PET) chemosensors and 2-ethyl-6-[(4-trifluoromethylphenylcarbamoyl)hydrazino]-benzo[de]iso-quinoline-1,3-dione, an amidourea-based sensor for anions. It has also been used in the synthesis of 1,8-naphthalimide based colorimetric and fluorescent sensor for anions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-(Trifluoromethyl)phenyl isocyanate has been used in the synthesis of fluorescent photoinduced electron transfer (PET) chemosensors and 2-ethyl-6-[(4-trifluoromethylphenylcarbamoyl)hydrazino]-benzo[de]iso-quinoline-1,3-dione, an amidourea-based sensor for anions. It has also been used in the synthesis of 1,8-naphthalimide based colorimetric and fluorescent sensor for anions.
Solubility
It hydrolyzes in water.
Notes
Moisture sensitive. Incompatible with oxidizing agents, alcohols, amines and heat.
RUO – Research Use Only
Thorfinnur Gunnlaugsson; Anthony P.Davis; John E O’Brien; Mark Glynn. Synthesis and photophysical evaluation of charge neutral thiourea or urea based fluorescent PET sensors for bis-carboxylates and pyrophosphate. Organic & Biomolecular Chemistry. 2005, 3,(1), 48-56.
Thorfinnur Gunnlaugsson; Paul E.Kruger; Paul Jensen; Juliann Tierney; Haslin Dato Paduka Ali; Gillian M.Hussey. Colorimetric “naked eye” sensing of anions in aqueous solution. J. Org. Chem. 2005, 70,(26), 10875-10878.