Thermo Scientific Chemicals

Benzyloxyacetyl chloride, 95%, Thermo Scientific Chemicals

Catalog number: L14337.14
25 g, Each
Thermo Scientific Chemicals

Benzyloxyacetyl chloride, 95%, Thermo Scientific Chemicals

Catalog number: L14337.14
25 g, Each
Quantity
Catalog number: L14337.14
also known as L14337-14
Price (USD)
Quantity
-
Have Questions?

Chemical Identifiers

CAS
19810-31-2
IUPAC Name
2-(benzyloxy)acetyl chloride
Molecular Formula
C9H9ClO2
InChI Key
QISAUDWTBBNJIR-UHFFFAOYSA-N
SMILES
ClC(=O)COCC1=CC=CC=C1
Form
liquid
Refractive Index
1.5195 - 1.5265
Appearance (Color)
Clear, colourless to pale yellow
Assay (Methyl Ester GC)
>94.0%

Description

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

Solubility
Reacts with water.

Notes
It is sensitive to moisture. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature is 2 - 8°C. Store under inert gas.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text