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7-Bromo-1-hydroxyisoquinoline, 97%, Thermo Scientific Chemicals
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Catalog number L17800.03
also known as L17800-03
Price (USD)/ Each
96.70
-
Quantity:
1 g
Price (USD)/ Each
96.70
7-Bromo-1-hydroxyisoquinoline, 97%, Thermo Scientific Chemicals
Catalog numberL17800.03
Price (USD)/ Each
96.70
-
Chemical Identifiers
CAS223671-15-6
IUPAC Name7-bromo-1,2-dihydroisoquinolin-1-one
Molecular FormulaC9H6BrNO
InChI KeyDSOKREQUHLPVFR-UHFFFAOYSA-N
SMILESBrC1=CC=C2C=CNC(=O)C2=C1
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Specifications
Specification Sheet
Specification SheetIdentification (FTIR)Conforms
Assay (HPLC)≥96.0%
Appearance (Color)Pale cream to yellow to brown
Melting Point (clear melt)245.5-251.5?C
FormPowder
7-Bromo-1-hydroxyisoquinoline acts as a pharmaceutical intermediate. It is also used to prepare 1-amino-4-bromoisoquinoline.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
7-Bromo-1-hydroxyisoquinoline acts as a pharmaceutical intermediate. It is also used to prepare 1-amino-4-bromoisoquinoline.
Solubility
Slightly soluble in water.
Notes
Incompatible with strong oxidizing agents.
7-Bromo-1-hydroxyisoquinoline acts as a pharmaceutical intermediate. It is also used to prepare 1-amino-4-bromoisoquinoline.
Solubility
Slightly soluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Ndubaku, C. O.; Crawford, T. D.; Chen, H.; Boggs, J. W.; Drobnick, J.; Harris, S. F.; Jesudason, R.; McNamara, E.; Nonomiya, J.; Sambrone, A.; Schmidt, S.; Smyczek, T.; Vitorino, P.; Wang, L.; Wu, P.; Yeung, S.; Chen, J.; Chen, K.; Ding, C. Z.; Wang, T.; Xu, Z.; Gould, S. E.; Murray, L. J.; Ye, W. Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. ACS Med. Chem. Lett. 2015, 6 (8), 913-918.
- Tikad, A.; Akssira, M.; Massip, S.; Léger, J. M.; Jarry, C.; Guillaumet, G.; Routier, S. Regiocontroled SNAr and Palladium Cross-Coupling Reactions of 2,4,7-Trichloropyrido[3,2-d]pyrimidine. Eur. J. Org. Chem. 2012, 2012 (24), 4523-4532.
- Price, D. A.; James, K.; Osborne, S.; Harbottle, G. W. Selective fluorination of 1-hydroxyisoquinolines using Selectfluor. Tetrahedron Lett. 2007, 48 (41), 7371-7373.