Potassium trans-beta-styryltrifluoroborate is used as a reactant for Suzuki-Miyaura cross-coupling, in enantioselective total synthesis of naseseazines A and B via regioselective Friedel-Crafts based arylative dimerization, in metal-free chlorodeboronation reactions, in preparation of aryl ketones via Lewis acid-catalyzed nucleophilic substitution and in preparation of Weinreb amides by palladium-catalyzed cross-coupling reactions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Potassium trans-beta-styryltrifluoroborate is used as a reactant for Suzuki-Miyaura cross-coupling, in enantioselective total synthesis of naseseazines A and B via regioselective Friedel-Crafts based arylative dimerization, in metal-free chlorodeboronation reactions, in preparation of aryl ketones via Lewis acid-catalyzed nucleophilic substitution and in preparation of Weinreb amides by palladium-catalyzed cross-coupling reactions.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- El Bakali, J., Maingot, L., Dumont, J., Host, H., Hocine, A., Cousaert, N., ... & Deprez-Poulain, R. (2012). Novel selective inhibitors of neutral endopeptidase: discovery by screening and hit-to-lead optimisation. MedChemComm, 3(4), 469-474.