2-Bromo-4-fluorobenzenesulfonyl chloride is used as a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Bromo-4-fluorobenzenesulfonyl chloride is used as a pharmaceutical intermediate.
Solubility
Hydrolyzes in water.
Notes
Moisture sensitive. Store away from oxidizing agents, water/ moisture, bases.
RUO – Research Use Only
General References:
- Ashit K. Ganguly; Sesha S. Alluri; Danielle Caroccia; Dipshikha Biswas; Chih-Hung Wang; Eunhee Kang; Yong Zhang; Andrew T. McPhail; Steven S. Carroll; Christine Burlein; Vandna Munshi; Peter Orth and Corey Strickland. Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors. J. Med. Chem. 2011, 54, (20), 7176-7183.
- Ashit K. Ganguly; Sesha S. Alluri; Chih-Hung Wang; Alyssa Antropow; Alex White; Danielle Caroccia; Dipshikha Biswas; Eunhee Kang; Li-Kang Zhang; Steven S. Carroll; Christine Burlein; John Fay; Peter Orthd, Corey Strickland.Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis. Tetrahedron. 2014, 70, (18), 2894-2904.