4-Iodobenzylamine hydrochloride is used to prepare cyclic amide by reacting with methyl 4-bromomethyl-3-methoxycarbonylcinnamate in the presence of triethylamine. It is also used in pharmaceuticals, agrochemicals and dye industries.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Iodobenzylamine hydrochloride is used to prepare cyclic amide by reacting with methyl 4-bromomethyl-3-methoxycarbonylcinnamate in the presence of triethylamine. It is also used in pharmaceuticals, agrochemicals and dye industries.
Solubility
Soluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Strack, M.; Langklotz, S.; Bandow, J. E.; Metzler-Nolte, N.; Albada, H. B. Silyl-Based Alkyne-Modifying Linker for the Preparation of C-Terminal Acetylene-Derivatized Protected Peptides. J. Org. Chem. 2012, 77 (22), 9954-9958.
- Wijtmans, M.; Verzijl, D.; Bergmans, S.; Lai, M.; Bosch, L.; Smit, M. J.; de Esch, I. J. P.; Leurs, R. CXCR3 antagonists: Quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors. Bioorg. Med. Chem. 2011, 19 (11), 3384-3393.