Muscimol, BODIPY™ TMR-X Conjugate

Muscimol is a powerful agonist of the GABA_A receptor and has been widely used to reversibly inactivate localized groups of neurons. The BODIPY TMR-X muscimol conjugate, can be used, in place of radioactive reagents and methods, to map the distribution of muscimol in the nervous system, as well as to detect the presence of GABA_A receptors on cell surfaces.

To make a concentrated stock solution, dissolve in either H₂O, buffer or normal saline (∼1 mM) or high quality anhydrous DMSO (∼2 mM). DMSO stock solutions should be stored frozen, desiccated and protected from light. Aqueous stock solution should be used fresh.