Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: PAARSMDSDS GEQSEGEPVT AAGPDV
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: TNF alpha-induced protein 8-like protein 3; TNFAIP8-like protein 3; Tumor necrosis factor alpha-induced protein 8-like protein 3; tumor necrosis factor, alpha induced protein 8 like 3; tumor necrosis factor, alpha-induced protein 8-like 3
Gene Aliases: TIPE3; TNFAIP8L3
UniProt ID: (Human) Q5GJ75
Entrez Gene ID: (Human) 388121
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