Search Thermo Fisher Scientific
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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PAKAAAASKK KPAGPSVSEL IVQAASSSKE RG
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H1 histone family, member 1; histone 1, H1a; Histone H1.1; Histone H1a
Gene Aliases: H1-1; H1.1; H1A; H1F1; HIST1; HIST1H1A
UniProt ID: (Human) Q02539
Entrez Gene ID: (Human) 3024
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