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Product Details
PA5-51896
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UBE2G2. Recombinant protein control fragment (Product #RP-102077).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649180
Product Specific Information
Immunogen sequence: LSFPLDYPLS PPKMRFTCEM FHPNIYPDGR VCISILHAPG DDPMGYESSA ERWSPVQSVE KILLSVVSML AEPNDESGAN VDASKMWRDD REQFYKIAKQ IVQKS
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme G2; Ubiquitin carrier protein G2; ubiquitin conjugating enzyme 7; ubiquitin conjugating enzyme E2G 2; ubiquitin conjugating enzyme G2; Ubiquitin-conjugating enzyme E2 G2; ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7); ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Ubiquitin-protein ligase G2
Gene Aliases: UBC7; UBE2G2
UniProt ID: (Human) P60604
Entrez Gene ID: (Human) 7327
ubiquitin-dependent protein catabolic process
protein N-linked glycosylation via asparagine
ER-associated ubiquitin-dependent protein catabolic process
cellular response to interferon-beta
cellular protein catabolic process
protein K48-linked ubiquitination
negative regulation of retrograde protein transport, ER to cytosol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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