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Invitrogen
GPR125 Polyclonal Antibody
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Product Details
PA5-52626
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GPR125. Recombinant protein control fragment (Product #RP-89573).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DIFRGLTNLV RLNLSGNLFS SLSQGTFDYL ASLRSLEFQT EYLLCDCNIL WMHRWVKEKN ITVRDTRCVY PKSLQAQPVT GVKQELLTCD PPLELPSFYM TPSHRQVVFE GDSLPFQCMA SYIDQDMQVL WYQDGRI
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor A3; G protein-coupled receptor 125; G-protein coupled receptor 125; probable G-protein coupled receptor 125
Gene Aliases: ADGRA3; GPR125; PGR21; TEM5L; UNQ556/PRO1113
UniProt ID: (Human) Q8IWK6
Entrez Gene ID: (Human) 166647
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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