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Product Details
PA5-53639
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CYP7B1. Recombinant protein control fragment (Product #RP-91048).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2640337
Product Specific Information
Immunogen sequence: VRDEIDRLLQ STGQKKGSGF PIHLTREQLD SLICLESSIF EALRLSSYST TIRFVEEDLT LSSETGDYCV RKGDLVAIFP PVLHGDPEIF EAPEEFRYDR FIEDGKKKTT FFKRGKKLKC YLMPFGTGTS KC
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 69%.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 24-hydroxycholesterol 7-alpha-hydroxylase; 25/26-hydroxycholesterol 7-alpha-hydroxylase; 3-hydroxysteroid 7-alpha hydroxylase; Cytochrome P450 7B1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1; Oxysterol 7-alpha-hydroxylase
Gene Aliases: CBAS3; CP7B; CYP7B1; SPG5A
UniProt ID: (Human) O75881
Entrez Gene ID: (Human) 9420
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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