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Product Details
PA5-53654
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human WDR39. Recombinant protein control fragment (Product #RP-91642).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649576
Product Specific Information
Immunogen sequence: CSDDRTVRIW RQYLPGNEQG VACSGSDPSW KCICTLSGFH SRTIYDIAWC QLTGALATAC GDDAIRVFQE DPNSDPQQPT FSLTAHLHQA HSQDVNCVAW NPKEPGLLAS CSDDGEVAFW KYQR
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
Target Information
WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CIAO1; cytosolic iron-sulfur protein assembly 1 homolog; Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat domain 39; WD repeat-containing protein 39; WD40 protein Ciao1
Gene Aliases: CIA1; CIAO1; WDR39
UniProt ID: (Human) O76071
Entrez Gene ID: (Human) 9391
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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