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Product Details
PA5-54708
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FAN. Recombinant protein control fragment (Product #RP-93730).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641497
Product Specific Information
Immunogen sequence: EKVAMLTQIL EFGQTPKQLF VTPHPRRITP KFKSLSQTSS YNASMADSPG EESFEDLTEE SKTLAWNNIT KLQLHEHYKI HKEAVTGITV SRNGSSVFTT
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 91%.
Target Information
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Factor associated with N-SMase activation; Factor associated with neutral sphingomyelinase activation; neutral sphingomyelinase (N-SMase) activation associated factor; Protein FAN
Gene Aliases: FAN; GRAMD5; NSMAF
UniProt ID: (Human) Q92636
Entrez Gene ID: (Human) 8439
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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