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Product Details
PA5-56088
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZRANB1. Recombinant protein control fragment (Product #RP-95811).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2650396
Product Specific Information
Immunogen sequence: SSGNSQRRSP PATKRDSEVK MDFQRIELAG AVGSKEELEV DFKKLKQIKN RMKKTDWLFL NACVGVVEGD LAAIEAYKSS GGDIARQLT
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp762P2216; hTrabid; TRAF-binding domain-containing protein; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; zinc finger, RAN-binding domain containing 1
Gene Aliases: TRABID; ZRANB1
UniProt ID: (Human) Q9UGI0
Entrez Gene ID: (Human) 54764
cytoskeleton organization
Wnt signaling pathway
cell migration
regulation of cell morphogenesis
positive regulation of Wnt signaling pathway
protein K29-linked deubiquitination
protein K63-linked deubiquitination
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
protein K33-linked deubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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