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            • Primary Antibodies ›
            • CPSF3 Antibodies

            Invitrogen

            CPSF3 Polyclonal Antibody

            View all (15) CPSF3 antibodies

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            Datasheet
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            Questions & Answers
            Catalog # PA5-57005
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            Cite CPSF3 Polyclonal Antibody

            • Antibody Testing Data (3)
            Application
            CPSF3 Antibody in Immunohistochemistry (IHC)
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            CPSF3 Antibody (PA5-57005) in IHC

            Immunohistochemical staining of CPSF3 in human gall bladder using a CPSF3 Polyclonal Antibody (Product # PA5-57005) shows strong nuclear and cytoplasmic positivity in glandular cells.
            View Product

            CPSF3 Antibody in Immunohistochemistry (IHC)
            CPSF3 Antibody in Western Blot (WB)
            CPSF3 Antibody in Western Blot (WB)
            CPSF3 Polyclonal Antibody

            Product Details

            PA5-57005

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.04-0.4 µg/mL
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human CPSF3. Recombinant protein control fragment (Product #RP-96050).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.3 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2640126

            Product Specific Information

            Immunogen sequence: PFNLLCYQLQ KLTGDVEELE IQEKPALKVF KNITVIQEPG MVVLEWLANP SNDMYADTVT TVILEVQSNP KIRKGAVQK

            Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

            Target Information

            Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006).

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: cleavage and polyadenylation specific factor 3, 73kDa; cleavage and polyadenylation specificity factor 3; Cleavage and polyadenylation specificity factor 73 kDa subunit; Cleavage and polyadenylation specificity factor subunit 3; CPSF; CPSF 73 kDa subunit; mRNA 3'-end-processing endonuclease CPSF-73; YSH1

            View more View less

            Gene Aliases: CPSF-73; CPSF3; CPSF73

            View more View less

            UniProt ID: (Human) Q9UKF6, (Mouse) Q9QXK7

            View more View less

            Entrez Gene ID: (Human) 51692, (Mouse) 54451, (Rat) 298916

            View more View less

            Function(s)

            RNA binding endoribonuclease activity protein binding 5'-3' exonuclease activity metal ion binding nuclease activity endonuclease activity hydrolase activity molecular_function RNA processing factor

            Process(es)

            mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA polyadenylation mRNA cleavage mRNA 3'-end processing by stem-loop binding and cleavage mRNA export from nucleus mRNA 3'-end processing RNA phosphodiester bond hydrolysis, endonucleolytic mRNA processing biological_process
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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