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Immunogen sequence: LYCAKYLPDI IKDQKAYKEG KLQKALEDAF LAIDAKLTTE EVIKELAQIA GRPTEDEDEK EKVADEDDVD
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fibroblast growth factor inducible 13; Fibroblast growth factor-inducible protein 13; FIN13; PP2C, gamma; PP2C-gamma; Protein phosphatase 1C; Protein phosphatase 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; protein phosphatase, Mg2+/Mn2+ dependent, 1G
Gene Aliases: AI385652; Fin13; PP2CG; PP2CGAMMA; PPM1C; PPM1G; PPP2CG
UniProt ID: (Human) O15355, (Mouse) Q61074
Entrez Gene ID: (Human) 5496, (Mouse) 14208, (Rat) 259229
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