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C1orf86 Antibody (PA5-58555) in WB
Western blot analysis of C1orf86 in control (vector only transfected HEK293T lysate) and C1orf86 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a C1orf86 Polyclonal Antibody (Product # PA5-58555).
Product Details
PA5-58555
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C1orf86. Recombinant protein control fragment (Product #RP-94374).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2638951
Product Specific Information
Immunogen sequence: GGHLESPARS LPQRPAPDPC RAPRVEQQPS VEGAAALRSC PMCQKEFAPR LTQLDVDSHL AQCLAESTED VTW
Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 55%.
Target Information
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FANCA-associated protein of 20 kDa; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa
Gene Aliases: C1orf86; FAAP20; FP7162
UniProt ID: (Human) Q6NZ36
Entrez Gene ID: (Human) 199990
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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