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Product Details
PA5-58638
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SPG20. Recombinant protein control fragment (Product #RP-97948).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647848
Product Specific Information
Immunogen sequence: AGAYMFPDTM LQAAGCFVGV VLSSELPEDD RELFEDLLRQ MSDLRLQANW NRAEEENEFQ IPGRTRPSSD QLKEASGTDV KQLDQGNKDV RHKGKRGKRA KDTSSE
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 74%.
Target Information
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Spartin; Spastic paraplegia 20 protein; Trans-activated by hepatitis C virus core protein 1
Gene Aliases: KIAA0610; SPART; SPARTIN; SPG20; TAHCCP1
UniProt ID: (Human) Q8N0X7
Entrez Gene ID: (Human) 23111
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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